Members

Bachta A

Backhaus M

Bong D

Bruyn GAW

Collado P

Damjanov N

Dejaco C

Delle-Sedie A

De Miguel E

Duftner C

Gessl I

Gutierrez M

Hammer HB

Hernandez-Diaz C

Iagnocco A

Ikeda K

Kane D

Keen H

Kelly S

Möller I

Moller-Døhn U

Naredo E

Nieto JC

Pineda C

Rodriguez A

Schmidt WA

Supp G

Szkudlarek M

Terslev L

Thiele R

Wakefield RJ

Windschall D

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Cartilage

Working group OMERACT > Overarching

 

MENTOR:

Maria-Antonietta D’Agostino

Convenors: Peter Mandl, Emilio Filippucci, Peter Balint

Objective of the subgroups work

  1. Development of a US scoring system for structural change in RA and other inflammatory arthritides

  2. Investigation of reliability, truth and feasibility

  3. Improve reliability and feasibility (which joints, which domains i.e. bone erosion, cartilage, joint deformity)

  4. After obtaining step 1-3, try endorsement of instrument

What is the contribution of the subgroup work to the OMERACT work?

This group combines the work of the erosion group and the cartilage group and aims to develop an instrument to measure structural damage in RA (and eventually in PsA)

 

Description of the previous work

Development and reliability testing of a semiquantitative scoring system (0-2) for grading cartilage changes in RA. The scoring system was shown to be reliable in MCP joints but reliability in PIP joints needs to be improved. Results were published:

Mandl P, Studenic P, Filippucci E, Bachta A, Backhaus M, Bong D, Bruyn GAW, Collado P, Damjanov N, Dejaco C, Delle-Sedie A, De Miguel E, Duftner C, Gessl I, Gutierrez M, Hammer HB, Hernandez-Diaz C, Iagnocco A, Ikeda K, Kane D, Keen H, Kelly S, Kővári E, Möller I, Møller-Dohn U, Naredo E, Nieto JC, Pineda C, Platzer A, Rodriguez A, Schmidt WA, Supp G, Szkudlarek M, Terslev L, Thiele R, Wakefield RJ, Windschall D, D'Agostino MA, Balint PV. Development of semiquantitative ultrasound scoring system to assess cartilage in rheumatoid arthritis. Rheumatology (Oxford). 2019 Apr 26. pii: kez153. doi:10.1093/rheumatology/kez153.

 

Reporting back of work done since ACR 2017

 

Next steps and discussion points

Next steps and discussion points cartilage

1.      Call for images of MCP joints with cartilage damage from patients in psoriatic arthritis and healthy controls, followed by web-based exercise to see whether the semiquantitative score can be adapted to PsA

2.       Call for images of PIP joints with cartilage damage from patients with RA and healthy controls, followed by web-based exercise

 

Next steps and discussion points structural damage

1.      SLR on the use of US to assess structural damage (early 2019)

2.      Call for images (summer 2019)

3.      Delphi (autumn 2019)

4.      Patient exercise (2020)